Kansas, North Carolina, Villanova and Duke occupied the four spots, putting some of the most historic programs in NCAA history under the spotlight. The 2022 Final Four was a prime example of why blue bloods are dependable commodities come tournament time. The best course of action would be to search for some lower seeds who are riding hot streaks entering March Madness, as they could be the key to setting your bracket apart from the pack. 1 seeds have made it to the national semifinal together just five times in the tournament's existence. The only time that occurred was in 2008, and three No.

Overall history suggests it's best to avoid a Final Four that contains all four No. In 2022, North Carolina made it to the National Championship against Kansas as a No. In recent years, we've seen teams seeded as low as No. 1 seeds to the Final Four and beyond, but picking all four to make it to the national semifinal would be a mistake. It's usually an easy decision to ride a few No.

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